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F Lehmann-Horn Selected Research

Hyperkalemic Periodic Paralysis

10/2011A novel N440K sodium channel mutation causes myotonia with exercise-induced weakness--exclusion of CLCN1 exon deletion/duplication by MLPA.
10/2006Muscle Na+ channelopathies: MRI detects intracellular 23Na accumulation during episodic weakness.
1/2000Different effects of mexiletine on two mutant sodium channels causing paramyotonia congenita and hyperkalemic periodic paralysis.

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F Lehmann-Horn Research Topics

Disease

7Malignant Hyperthermia
09/2014 - 01/2000
5Contracture
09/2014 - 11/2000
5Myotonia
10/2011 - 08/2000
4Paralysis (Palsy)
04/2011 - 12/2000
4Channelopathies
10/2010 - 01/2001
3Hyperkalemic Periodic Paralysis
10/2011 - 01/2000
3Muscular Diseases (Myopathy)
04/2011 - 01/2000
3Hypokalemic Periodic Paralysis (Periodic Paralysis, Hypokalemic)
11/2004 - 08/2000
3Epilepsy (Aura)
06/2001 - 12/2000
2Edema (Dropsy)
11/2012 - 06/2005
2Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker)
11/2012 - 12/2011
2Myotonic Disorders (Paramyotonia Congenita)
10/2011 - 01/2000
2Potassium aggravated myotonia
10/2011 - 10/2006
2Central Core Myopathy (Central Core Disease)
12/2008 - 12/2001
2Muscle Weakness
06/2001 - 08/2000
1Type 2 Episodic Ataxia
07/2011
1Ataxia (Dyssynergia)
07/2011
1Diarrhea
03/2009
1Hyperhidrosis
03/2009
1Myotonic Dystrophy (Dystrophia Myotonica)
12/2008
1Myotonia Congenita (Thomsen Disease)
12/2008
1Andersen Syndrome
10/2005
1familial type 2 Hemiplegic migraine
05/2004
1Migraine with Aura (Familial Hemiplegic Migraine)
05/2004
1Heart Arrest (Cardiac Arrest)
03/2002
1Charcot-Marie-Tooth Disease (Peroneal Muscular Atrophy)
03/2002
1Hypothermia
03/2002
1Myasthenia Gravis
02/2002
1Inborn Genetic Diseases (Disease, Hereditary)
06/2001
1Epileptic Syndromes
01/2001
1Episodic Ataxia
01/2001
1Autosomal Dominant Nocturnal Frontal Lobe Epilepsy
01/2001
1Generalized Epilepsy with Febrile Seizures Plus
01/2001
1Benign Neonatal Epilepsy (Benign Familial Neonatal Convulsions)
01/2001
1Seizures (Absence Seizure)
12/2000
1Osteochondrodysplasias (Spondyloepiphyseal Dysplasia)
12/2000
1Type 2 Hypokalemic Periodic Paralysis
08/2000

Drug/Important Bio-Agent (IBA)

7Sodium Channels (Sodium Channel)IBA
10/2011 - 01/2000
4Ion Channels (Ion Channel)IBA
04/2011 - 01/2001
3Caffeine (No Doz)FDA LinkGeneric
09/2014 - 07/2003
3Halothane (Fluothane)FDA Link
09/2014 - 07/2003
3Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)IBA
09/2013 - 08/2000
3SodiumIBA
11/2012 - 12/2000
3Acetazolamide (Diamox)FDA LinkGeneric
03/2009 - 06/2001
2PotassiumIBA
10/2011 - 06/2001
2Potassium Channels (Potassium Channel)IBA
10/2005 - 01/2001
2Pharmaceutical PreparationsIBA
07/2003 - 01/2000
2Succinylcholine (Suxamethonium Chloride)FDA LinkGeneric
03/2002 - 02/2002
2CalciumIBA
12/2001 - 01/2000
2Voltage-Gated Sodium ChannelsIBA
06/2001 - 01/2001
2Anticonvulsants (Antiepileptic Drugs)IBA
01/2001 - 12/2000
1Eplerenone (Inspra)FDA LinkGeneric
11/2012
1Chloride Channels (Chloride Channel)IBA
10/2011
14-Aminopyridine (4 Aminopyridine)FDA Link
07/2011
1Therapeutic UsesIBA
07/2011
1antineoplaston A10 (A 10)IBA
10/2006
1GadoliniumIBA
06/2005
1Biological ProductsIBA
01/2005
1Adenosine Triphosphatases (ATPase)IBA
05/2004
1Thiopental (Pentothal)FDA Link
03/2002
1Cholinesterase Inhibitors (Anticholinesterases)IBA
03/2002
1Codon (Codons)IBA
06/2001
1KCNQ Potassium ChannelsIBA
01/2001
1ezogabine (retigabine)IBA
01/2001
1GABA-A Receptors (GABA(A) Receptor)IBA
01/2001
1Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA
01/2001
1Voltage-Gated Potassium Channels (Voltage-Gated Potassium Channel)IBA
01/2001
1Proteoglycans (Proteoglycan)IBA
12/2000
1perlecanIBA
12/2000
1XenonIBA
11/2000
1L-Type Calcium Channels (Dihydropyridine Receptor)IBA
08/2000
1Proteins (Proteins, Gene)FDA Link
08/2000
1Anesthetics (Anesthetic Agents)IBA
01/2000
1Mexiletine (Mexitil)FDA LinkGeneric
01/2000

Therapy/Procedure

3Therapeutics
12/2008 - 12/2000
1Activities of Daily Living (ADL)
07/2011
1Anesthesia
01/2000